No, a Muslim can not drink wine and other alcoholic beverages, as the Qur’an clearly forbids it.
“They ask you about intoxicants and games of chance. Say: In both of them there is a great sin and means of profit for men, and their sin is greater than their profit. And they ask you as to what they should spend. Say: What you can spare. Thus does Allah make clear to you the communications, that you may ponder.” (2:219)
As far as smoking is concerned, the opinion of some Mujtahids might differ. For example; Ayatullah Fadhlullah has declared smoking as haram. Others will say that it is haram to start and get addicted to it in the first place. And some might say that it is haram once the person is aware of the damage being done on his body from smoking.